Charles River Laboratories International, Inc.
Location
Massachusetts
Founded
1947-02-28
Website
Risk Signals
1070 news mentions monitored
Industry Context
This company is tracked across risk categories, including those related to its sector (e.g., Commercial Physical and Biological Research, Testing Laboratories), including supply chain integrity, ESG practices, labor disputes, and regulatory compliance.
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Recent Articles about Charles River Laboratories International, Inc.
Live alerts from global media, monitored by Business Radar
2024-01-17 (breitbart.com)
Plan for $400 million monkey-breeding facility in southwest Georgia draws protest - Breitbart
Some local residents and an animal-rights group are protesting plans for a monkey-breeding facility in southwest Georgia Plan for $400 million
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2023-12-05 (nature.com)
Investigation of monoclonal antibody CSX-1004 for fentanyl overdose
The opioid crisis in the United States is primarily driven by the highly potent synthetic opioid fentanyl leading to >70,000 overdose deaths annually; thus, new therapies for fentanyl overdose are urgently needed. Here, we present the first clinic-ready, fully human monoclonal antibody CSX-1004 with picomolar affinity for fentanyl and related analogs. In mice CSX-1004 reverses fentanyl antinociception and the intractable respiratory depression caused by the ultrapotent opioid carfentanil. Moreover, toxicokinetic evaluation in a repeat-dose rat study and human tissue cross-reactivity study reveals a favorable pharmacokinetic profile of CSX-1004 with no safety-related issues. Using a highly translational non-human primate (NHP) model of respiratory depression, we demonstrate CSX-1004-mediated protection from repeated fentanyl challenges for 3-4 weeks.
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2023-11-03 (midlothianadvertiser.co.uk)
East Lothian crime: Animal rights protestor claims she was hit by car during silent protest
Rachel Cambell was part of a silent protest when she said she was hit by the vehicle.
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2023-11-02 (edinburghlive.co.uk)
East Lothian animal rights protestor 'struck by car' outside medical lab
A woman who was part of a silent protest for animal rights in East Lothian claims she was "struck by a car and had to be taken to hospital" for treatment to injuries to her legs and back.
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2019-03-18 (detroitnews.com)
Humane society: Halt on beagle lab testing a 'huge win'
Lab 'immediately ended study ... and will make every effort to rehome the animals that were part of the study,' says Corteva Agriscience
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