RENEWABLE ENERGY SYSTEMS LIMITED

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Pathogenic role of acyl coenzyme A binding protein (ACBP) in Cushing’s syndrome

2024-11-22 (nature.com)

Pathogenic role of acyl coenzyme A binding protein (ACBP) in Cushing’s syndrome

Cushing’s syndrome is caused by an elevation of endogenous or pharmacologically administered glucocorticoids. Acyl coenzyme A binding protein (ACBP, encoded by the gene diazepam binding inhibitor, Dbi) stimulates food intake and lipo-anabolic reactions. Here we found that plasma ACBP/DBI concentrations were elevated in patients and mice with Cushing’s syndrome. We used several methods for ACBP/DBI inhibition in mice, namely, (1) induction of ACBP/DBI autoantibodies, (2) injection of a neutralizing monoclonal antibody, (3) body-wide or hepatocyte-specific knockout of the Dbi gene, (4) mutation of the ACBP/DBI receptor Gabrg2 and (5) injections of triiodothyronine or (6) the thyroid hormone receptor-β agonist resmetirom to block Dbi transcription. These six approaches abolished manifestations of Cushing’s syndrome such as increased food intake, weight gain, excessive adiposity, liver damage, hypertriglyceridaemia and type 2 diabetes.

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Community football club changing rooms get a boost

2024-09-17 (aberdeenbusinessnews.co.uk)

Community football club changing rooms get a boost

BANCHORY Community Football Club has received a £5,000 grant from renewable company, RES, to help refurbish their water-damaged changing rooms.

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Highland Council objection to revised Dava Moor wind farm plan triggers public inquiry

2022-02-10 (strathspey-herald.co.uk)

Highland Council objection to revised Dava Moor wind farm plan triggers public inquiry

'It is like saying you have planning permission for a bungalow and then changing it to a four storey building'

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Fundamental transport mechanisms, fabrication and potential applications of nanoporous atomically thin membranes |  Nanotechnology

2017-06-06 (nature.com)

Fundamental transport mechanisms, fabrication and potential applications of nanoporous atomically thin membranes | Nanotechnology

This Review examines the development of nanoporous atomically thin membranes, focusing on fundamental mechanisms of gas- and liquid-phase transport, membrane fabrication techniques, and advances towards practical applications. Graphene and other two-dimensional materials offer a new approach to controlling mass transport at the nanoscale. These materials can sustain nanoscale pores in their rigid lattices and due to their minimum possible material thickness, high mechanical strength and chemical robustness, they could be used to address persistent challenges in membrane separations. Here we discuss theoretical and experimental developments in the emerging field of nanoporous atomically thin membranes, focusing on the fundamental mechanisms of gas- and liquid-phase transport, membrane fabrication techniques and advances towards practical application. We highlight potential functional characteristics of the membranes and discuss applications where they are expected to offer advantages.

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Storm of protest on wind farm scheme

1997-10-08 (heraldscotland.com)

Storm of protest on wind farm scheme

A PUBLIC inquiry into proposals to erect 38 of the tallest windmills in the UK on three wind farms on the hills above Helmsdale opened yesterday in…

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Solar-powered technology converts saltwater into drinking water emission-free

(electronicspecifier.com)

Solar-powered technology converts saltwater into drinking water emission-free

Scientists have developed a new solar-powered system to convert saltwater into fresh drinking water which they say could help reduce dangerous waterborne diseases like cholera.

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